HPLC Column

A Solid-Core Particle that Lives Up to Its Potential.


State-of-the-art Reversed-Phase and HILIC HPLC Columns

Waters offers a wide range of analytical and preparative chromatography columns to meet the needs of virtually every application. The Waters Column Advisor recommends the most appropriate column depending on the on the application requirements you need to consider and the column characteristics you are looking for. Separations developed on our analytical columns can be directly scaled up to preparative columns. We supply a wide range of phase chemistries in numerous column dimensions for preparative work to meet your scale-up needs. All chromatography columns meet stringent specifications to ensure excellent performance and column-to-column reproducibility. We also offer a wide range of accessories to support these columns.


Cortecs Columns

Based on 1.6 µm and 2.7 µm solid-core particle technology, CORTECS Columns enable you to achieve new levels  of efficiency and performance.

XBridge Columns

Designed for maximum method development flexibility and fast purification. Develop robust methods for both small molecules as well as more complex biopharmaceuticals across a broad range of pH values, temperatures, and eluent choices.

XSelect Columns

The proprietary Charged Surface Hybrid (CSH) Technology that powers XSelect Columns improves selectivity and offers the highest possible performance for basic compounds in the acidic, low ionic strength mobile phases commonly used in LC-MS laboratories.

VanGuard Columns Protection

VanGuard Column Pre-columns and Cartridges are optimized to protect and prolong analytical column lifetimes without compromising chromatographic performance.

Symmetry Columns

Symmetry LC columns manufactured using high purity silica and tightly controlled manufacturing processes to ensure that you receive a column that exceeds the standards for HPLC column performance.

Atlantis Columns

Atlantis analytical and preparative columns are the industry-leading solution for polar compound retention.

SunFire Columns

SunFire Chromatography Columns are available in analytical and preparative dimensions and feature state-of-the-art bonded-silica designed for high mass loading capability, excellent low pH stability, superior peak shapes, and high efficiency.

Exterra Columns

Based upon first generation hybrid (inorganic/organic) particles, the XTerra family of HPLC columns enables chromatographers to perform high pH drug discovery, method development and purification separations.

Column Accessories

Waters offers a variety of tubings, fittings, column connections, and replacement parts for columns and cartridges.


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